WebFor instance, in breast cancer, the CD24 −/lo /epithelial cell adhesion molecule (EpCAM) lo CSC phenotype resembles that of CD49f + /ESA −/lo normal human mammary stem cell 11,12 and aldehyde dehydrogenase 1 (ALDH1), a marker of normal mammary stem cells, is a well-established breast cancer stem cell (BCSC) marker. 13 It is proposed that ... WebDec 22, 2015 · Representative capturing upon coupling to anti-EpCAM, anti-Trop2 and anti-CD49f of pooled EpCAM pos as well as EpCAM low/neg cells is displayed in Fig 4. …
Dissecting the mammary gland one cell at a time - Nature
Web暨南大学,数字图书馆. 开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebSep 2, 2010 · As expected on the basis of our previous genomic analysis of the differentiation status of these cell lines, virtually all claudin-low SUM159PT cells showed a stromal or MaSC antigenic phenotype (CD49f + /EpCAM-), ~98% of MCF-7 cells showed a mL phenotype (CD49f-/low /EpCAM +), and ~83% of SUM149PT cells showed a pL … hoist the colours paroles
Mapping the cellular and molecular heterogeneity of …
WebNov 3, 2024 · CD49f + /EpCAM −, CD49f + /EpCAM +, and CD49f − /EpCAM + cells are considered to enrich for basal/stem, luminal progenitors, and mature/differentiated cells, respectively . The CD49f/EpCAM staining pattern revealed the presence of higher levels of CD49f + /EpCAM − basal/stem cells in milk of the breast with cancer (right breast) … WebApr 14, 2024 · D, KTB103 TONSL-overexpressing cells are predominantly luminal progenitors based on CD49f and EpCAM staining pattern (CD49f + /EpCAM +). Primary KTB103 cells contained luminal progenitor and basal/stem cell subpopulation. E, Only HRas G12V plus SV40-T/t antigen–overexpressing cells generated tumors in NSG mice. … WebJan 14, 2014 · Mesenchymal-like BCSCs characterized as CD24 − CD44 + are primarily quiescent and localized at the tumor invasive front, whereas epithelial-like BCSCs express aldehyde dehydrogenase (ALDH), are proliferative, and are located more centrally. huckeby real estate